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Standardization of an Encapsulation System: A Method to Remove Fragile Cells

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 326))

Abstract

Erythrocytes have been proposed and utilized as carriers for drugs, enzymes and pharmacological agents.1–13 Carrier erythrocytes have the capacity to enhance drug efficacy, extend the pharmacological life span of the drug, and reduce toxic side effects. Hypotonic dialysis has been used to prepare carriers that have a high percentage of encapsulation and cell recovery, and a normal survival when they are reinjected into the animal.1,2

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© 1992 Springer Science+Business Media New York

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Chiarantini, L., DeLoach, J.R. (1992). Standardization of an Encapsulation System: A Method to Remove Fragile Cells. In: Magnani, M., DeLoach, J.R. (eds) The Use of Resealed Erythrocytes as Carriers and Bioreactors. Advances in Experimental Medicine and Biology, vol 326. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3030-5_7

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  • DOI: https://doi.org/10.1007/978-1-4615-3030-5_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6321-7

  • Online ISBN: 978-1-4615-3030-5

  • eBook Packages: Springer Book Archive

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