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Transplant-Mediated Recovery of Innervation and Function: The Habenulo-Interpeduncular System of the Rat

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Development of the Central Nervous System in Vertebrates

Part of the book series: NATO ASI Series ((NSSA,volume 234))

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Abstract

Transplants of fetal cells into host brains can be used to examine the development of specific afferent projections and can also provide a means of repairing brain damage and thereby restoring function after injury. Restoration of function mediated by transplanted tissue provides compelling evidence that the implanted cells have integrated functionally in the host brain. We have used transplants of fetal tissue into host brains whose interpeduncular nuclei have been denervated by bilateral lesions to the fasciculus retroflexus, firstly to examine some of the features regulating innervation of the interpeduncular nucleus in the rat and, secondly, to characterize the functional organization of this system.

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© 1992 Springer Science+Business Media New York

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Murray, M., Eckenrode, T.C., Haun, F. (1992). Transplant-Mediated Recovery of Innervation and Function: The Habenulo-Interpeduncular System of the Rat. In: Sharma, S.C., Goffinet, A.M. (eds) Development of the Central Nervous System in Vertebrates. NATO ASI Series, vol 234. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3018-3_18

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  • DOI: https://doi.org/10.1007/978-1-4615-3018-3_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6315-6

  • Online ISBN: 978-1-4615-3018-3

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