Abstract
Mouse hepatitis virus (MHV), a coronavirus, contains an approximately 31 kb-long genomic RNA (8, 9). In MHV-infected cells, seven to eight species of virus-specific subgenomic mRNAs with a 3’-coterminal nested-set structure (6, 10) are synthesized; these are numbered 1 to 7, in decreasing order of size (6, 10). The 5’-end of MHV genomic RNA contains a 72- to 77-nucleotide-long leader sequence (5, 7, 22). An identical sequence is found at the 5’-end of each MHV mRNA species; in each, the leader sequence is fused with the mRNA body sequence, which starts from a consensus sequence at the intergenic sites (17, 21).
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Kim, YN., Lai, M.M.C., Makino, S. (1994). Site-Specific Sequence Repair of Coronavirus Defective Interfering RNA by RNA Recombination and Edited RNA. In: Laude, H., Vautherot, JF. (eds) Coronaviruses. Advances in Experimental Medicine and Biology, vol 342. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2996-5_22
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DOI: https://doi.org/10.1007/978-1-4615-2996-5_22
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