Abstract
Previous studies have demonstrated that the MHV genome is divided into seven transcriptional units which are transcribed from highly conserved intergenic start sites (UCU/CAAAC) into mRNA containing a common leader RNA at the 5’ end and a coterminal 3’ end. In this manuscript, we provide evidence that an additional transcriptional unit is encoded at the 3’ end of the MHV genome and is transcribed from a perfect intergenic region into a leader-containing ~800 nt mRNA. This mRNA could potentially encode a small 17–18 kDa protein which is identical to the C-terminal third of the nucleocapsid gene.
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© 1994 Springer Science+Business Media New York
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Schaad, M.C., Chen, W., Peel, S.A., Baric, R.S. (1994). Studies into the Mechanism for MHV Transcription. In: Laude, H., Vautherot, JF. (eds) Coronaviruses. Advances in Experimental Medicine and Biology, vol 342. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2996-5_14
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DOI: https://doi.org/10.1007/978-1-4615-2996-5_14
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