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Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in the Zucker Fatty Rat: A Case for Differential Tissue Regulation

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Current Directions in Insulin-Like Growth Factor Research

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 343))

Abstract

Obesity is one of the most common health care problems in the Western world.1 It is associated with hypertension, hyperlipidemia and a predisposition to Type II Diabetes Mellitus, which probably accounts, in part, for the high risk these patients have of accelerated atherosclerosis. Given the numbers of people affected and the predisposition these patients have to multiple medical problems, an understanding of the pathophysiology involved in the causes for, and perpetuation of, obesity would aid our ability to possibly prevent and more effectively treat this disease.

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Author information

Authors and Affiliations

  1. Division of Endocrinology and Metabolism, Department of Medicine, SUNY, Stony Brook, NY, 11794, USA

    Marie C. Gelato & Michael Berelowitz

Authors
  1. Marie C. Gelato
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  2. Michael Berelowitz
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Editor information

Editors and Affiliations

  1. National Institutes of Health, Bethesda, Maryland, USA

    Derek Le Roith M.D., Ph.D.

  2. University of Florida, Gainesville, Florida, USA

    Mohan K. Raizada Ph.D.

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© 1994 Springer Science+Business Media New York

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Gelato, M.C., Berelowitz, M. (1994). Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in the Zucker Fatty Rat: A Case for Differential Tissue Regulation. In: Le Roith, D., Raizada, M.K. (eds) Current Directions in Insulin-Like Growth Factor Research. Advances in Experimental Medicine and Biology, vol 343. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2988-0_36

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  • DOI: https://doi.org/10.1007/978-1-4615-2988-0_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6301-9

  • Online ISBN: 978-1-4615-2988-0

  • eBook Packages: Springer Book Archive

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