Abstract
The search for classic opiate receptors on cells of the human immune system has been essentially futile (1,2). However, a large block of replicable data have suggested that opiates are potent modulators of immune status or function. This quandary has been partially resolved by the demonstration of non-classic opiate binding sites or situational binding sites on cellular elements of the immune system. These sites appear to be highly ligand specific; but their pattern of specificity does not mirror those of the opiate receptors of the central nervous system (CNS).
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© 1993 Springer Science+Business Media New York
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Madden, J.J., Ketelsen, D., Whaley, W.L. (1993). Morphine Binding Sites on Human T Lymphocytes. In: Friedman, H., Klein, T.W., Specter, S. (eds) Drugs of Abuse, Immunity, and AIDS. Advances in Experimental Medicine and Biology, vol 335. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2980-4_9
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DOI: https://doi.org/10.1007/978-1-4615-2980-4_9
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