Abstract
Recent studies using a quantitative image analysis technique (Clarke, Daly & Ead 1990) have shown that the vascular compartment of the carotid body may be analysed with special reference to the vessels whose diameters lie between 5µm and 12µm. It is well known that in the spontaneously hypertensive rat (SHR) the carotid bodies are enlarged (Habeck 1991). Accordingly we have applied this technique to the analysis of the carotid body in these SHR animals to determine the contribution of the vascular compartment to the increase in volume. In this study the volumes of the carotid body and its vascular compartment were studied during postnatal maturation of the control and SHR animals. The vascular compartment was divided into that containing small vessels (diameter 5µm - 12µm) and that containing vessels greater than 12µm in diameter.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Clarke J.A. & Daly M. de B. : Distribution of carotid body type I cells and other periadventitial type I cells in the carotid body bifurcation regions of the cat. Anat. Embryol. 166: 169–189 (1983).
Clarke J.A. & Daly M. de B.: The volume of the carotid body and periadventitial type I and II cells in the carotid bifurcation region of the fetal cat and kitten. Anat. Embryol. 173: 117–127 (1985).
Clarke J A., Daly M. de B. & Ead H.W: Comparison of the size of the vascular compartment of the carotid body of the fetal, neonatal and adult cat. Acta Anat 138: 166–174 (1990).
Fukada,Y, Sato, A & Trzebski, A.: Carotid chemoreceptor discharge responses to hypoxia and hypercapnia in normotensive and spontaneously hypertensive rats. J. Autonom. Nerve Syst. 19: 1–11 (1987).
Habeck,J.-O., Huckstorf C.& Honig, A.: Influence of age on the carotid bodies of spontaneously hypertensive (SHR) and normotensive rats. Exp. Path. 27:79–89 (1985).
Habeck, J.-O.: Peripheral arterial chemoreceptors and hypertension. J. Autonom. Nerve Syst. 34: 1–8 (1991).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer Science+Business Media New York
About this chapter
Cite this chapter
Clarke, J.A., de Daly, M.B., Ead, H.W. (1993). Vascular Analysis of the Carotid Body in the Spontaneously Hypertensive Rat. In: Data, P.G., Acker, H., Lahiri, S. (eds) Neurobiology and Cell Physiology of Chemoreception. Advances in Experimental Medicine and Biology, vol 337. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2966-8_1
Download citation
DOI: https://doi.org/10.1007/978-1-4615-2966-8_1
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6290-6
Online ISBN: 978-1-4615-2966-8
eBook Packages: Springer Book Archive