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Object Oriented Simulation of Metabolic Processes

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Modern Trends in Biothermokinetics

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Abstract

Simulation of metabolic processes in cells is usually done by solving sets of coupled differential equations (using software systems like for instance SCoP1 or MLAB2). Each equation represents the change per unit of time in the concentration of a certain metabolite or other substance. Such a rate of change depends on the rates of all chemical reactions that produce or consume that substance. In the modeling and simulation approach we present here, we focus on the essential independence of the underlying reactions.

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References

  1. J. M. Kootsey. “Introduction to Computer Simulation,” National Biomedical Simulation Resource, Duke University Medical Center (NC) (1989).

    Google Scholar 

  2. B. Bunow and G. Knott. “MLAB, A Mathematical Modeling Laboratory,” Civilized Software, Bethesda (MD) (1990).

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  3. L. J. Pinson and R. S. Wiener. “An Introduction to Object Oriented Programming and Smalltalk,” Addison-Wesley, Reading (MA) (1988).

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  4. M. A. Ellis and B. Stroustrup. “The Annotated C++ Reference Manual,” Addison-Wesley, Reading, MA(1990).

    Google Scholar 

  5. A. L. Lehninger. “Biochemistry,” Worth Publishers, New York (1970).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Divisions of Molecular Biology and Biophysics, The Netherlands Cancer Institute, Plesmanlaan 121, NL-1066 CX, Amsterdam, The Netherlands

    H. J. Stoffers, B. van Stigt, P. Richard, A. A. van der Gugten, H. V. Westerhoff & G. J. F. Blommestijn

Authors
  1. H. J. Stoffers
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  2. B. van Stigt
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  3. P. Richard
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  4. A. A. van der Gugten
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  5. H. V. Westerhoff
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  6. G. J. F. Blommestijn
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Editor information

Editors and Affiliations

  1. University of Bordeaux II, Bordeaux, France

    Stefan Schuster , Rachid Ouhabi  & Jean-Pierre Mazat ,  & 

  2. Institute of Cellular Biochemistry, CNRS, Bordeaux, France

    Michel Rigoulet

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© 1993 Springer Science+Business Media New York

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Stoffers, H.J., van Stigt, B., Richard, P., van der Gugten, A.A., Westerhoff, H.V., Blommestijn, G.J.F. (1993). Object Oriented Simulation of Metabolic Processes. In: Schuster, S., Rigoulet, M., Ouhabi, R., Mazat, JP. (eds) Modern Trends in Biothermokinetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2962-0_74

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  • DOI: https://doi.org/10.1007/978-1-4615-2962-0_74

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6288-3

  • Online ISBN: 978-1-4615-2962-0

  • eBook Packages: Springer Book Archive

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