Abstract
Quantitative approaches have led to appreciable advances in understanding the control of cellular metabolism1–3. In the framework of this approach the contribution of any enzyme (E i ) to the control of the flux (J) is characterized by its control coefficient defined in terms of the fractional change ∂J / J in the metabolic flux induced by the fractional change ∂E i / E i in the enzyme concentration:
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Kholodenko, B.N., Westerhoff, H.V. (1993). Sum of the Flux Control Coefficients: What is it Equal to in Different Systems?. In: Schuster, S., Rigoulet, M., Ouhabi, R., Mazat, JP. (eds) Modern Trends in Biothermokinetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2962-0_33
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DOI: https://doi.org/10.1007/978-1-4615-2962-0_33
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