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Monocyte Chemotactic Proteins Related to Human MCP-1

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The Chemokines

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 351))

Abstract

This study describes the isolation and identification of two novel monocyte chemotactic factors from human tumor cells. Since the corresponding 7.5 kD and 11 kD proteins show high structural and functional similarity with MCP-1 (1) they are designated MCP-2 and MCP-3, respectively. Based on the conservation of four cysteine residues, these molecules can be classified in the chemokine family.

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Author information

Authors and Affiliations

  1. Rega Institute for Medical Research, University of Leuven, B-3000, Leuven, Belgium

    Jo Van Damme, Paul Proost, Jean-Pierre Lenaerts, René Conings, Ghislain Opdenakker & Alfons Billiau

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  1. Jo Van Damme
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  2. Paul Proost
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  3. Jean-Pierre Lenaerts
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  4. René Conings
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  5. Ghislain Opdenakker
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  6. Alfons Billiau
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Editor information

Editors and Affiliations

  1. Sandoz Research Institute, Vienna, Austria

    I. J. D. Lindley

  2. University of Bath, Bath, UK

    J. Westwick

  3. University of Michigan, Ann Arbor, Michigan, USA

    S. Kunkel

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© 1993 Springer Science+Business Media New York

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Van Damme, J., Proost, P., Lenaerts, JP., Conings, R., Opdenakker, G., Billiau, A. (1993). Monocyte Chemotactic Proteins Related to Human MCP-1. In: Lindley, I.J.D., Westwick, J., Kunkel, S. (eds) The Chemokines. Advances in Experimental Medicine and Biology, vol 351. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2952-1_12

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  • DOI: https://doi.org/10.1007/978-1-4615-2952-1_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6283-8

  • Online ISBN: 978-1-4615-2952-1

  • eBook Packages: Springer Book Archive

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