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The Mammalian Cochlear Nuclei pp 361–371Cite as

Physiology of the Dorsal Cochlear Nucleus Molecular Layer

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Part of the book series: NATO ASI series ((NSSA,volume 239))

Abstract

The dorsal cochlear nucleus (DCN) is a complex but elegantly organized division of the cochlear nucleus. Lorente de Nó (’81) recognized that the cortex of the nucleus (layers 1 and 2) bore a remarkable resemblance to the cerebellum, in both the structural characteristics of the cells and their organization. The chief organization of the nucleus is based on a concentric laminar arrangement of cells, their dendrites, and fiber systems, somewhat like a single cerebellar folium. A local cartesian framework can be imposed on the nucleus, where the principal axes are depth (perpendicular to the local surface), the striai axis (parallel to the long axis of the nucleus and to the unmyelinated parallel fibers in the molecular layer), and the transstriai axis (parallel to the isofrequency planes formed by the auditory nerve fibers). Subsequent anatomical studies have exposed further similarities between the outer layers of the DCN and the cerebellum. Although the two structures serve different functions, the common ontogenetic origins and parallel expression of proteins in corresponding cell types (Mugnaini and Morgan,’ 87; Mugnaini et al.,’ 87; Berrebi and Mugnaini, this volume; Berrebi et al.,’ 90) suggests that the two structures share some mechanisms of information processing.

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Author information

Authors and Affiliations

  1. Departments of Otolaryngology-Head and Neck Surgery, Neuroscience and Biomedical Engineering, and The Center for Hearing Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA

    Paul B. Manis & John C. Scott

  2. Department of Otolaryngology, West Virginia University School of Medicine, Morgantown, WV, 26506, USA

    George A. Spirou

Authors
  1. Paul B. Manis
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  2. John C. Scott
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  3. George A. Spirou
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Editor information

Editors and Affiliations

  1. University of Salamanca, Salamanca, Spain

    Miguel A. Merchán

  2. University of Alicante, Alicante, Spain

    José M. Juiz

  3. Medical College of Ohio, Toledo, Ohio, USA

    Donald A. Godfrey

  4. University of Connecticut, Storrs, Connecticut, USA

    Enrico Mugnaini

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© 1993 Springer Science+Business Media New York

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Manis, P.B., Scott, J.C., Spirou, G.A. (1993). Physiology of the Dorsal Cochlear Nucleus Molecular Layer. In: Merchán, M.A., Juiz, J.M., Godfrey, D.A., Mugnaini, E. (eds) The Mammalian Cochlear Nuclei. NATO ASI series, vol 239. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2932-3_28

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  • DOI: https://doi.org/10.1007/978-1-4615-2932-3_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6273-9

  • Online ISBN: 978-1-4615-2932-3

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