Adhesion Molecules: Co-Stimulators and Co-Mitogens in Dendritic Cell - T Cell Interaction

  • Philip D. King
  • Mohammad A. A. Ibrahim
  • David R. Katz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)


Dendritic cells (DC) are identified both by morphology and function (1-3). These cells are localised to T cell micro-environments and are the most potent known accessory inducer cells for T cell responses. Even when there is heterogeneity in in vitro comparative accessory cell function (i. e. when more than one cell type can present), then the DC almost invariably prove to be the most potent relative inducers (4, 5). Thus the distinguishing molecular mechanisms involved in DC — T cell interaction that might account for this distinctive inducer capacity is obviously of considerable interest.


Dendritic Cell Sodium Periodate Dendritic Cell Function Distinguishing Molecular Mechanism Mouse Dendritic Cell 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Philip D. King
    • 1
  • Mohammad A. A. Ibrahim
    • 1
  • David R. Katz
    • 1
  1. 1.Depts of HistopathologyImmunology and Biology University College and Middlesex School of MedicineLondonUK

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