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Dendritic Cells are Potent Antigen-Presenting Cells for Microbial Superantigen

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Dendritic Cells in Fundamental and Clinical Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 329))

Summary

Dendritic cells (DC) were found to be more efficient than macrophages (MO) in activating T cell responses to Staphylococcal enterotoxin B (SEB) using the hanging drop techniques and DC as antigen presenting cells (APC). When superantigen was presented via DC, the activation of T cells was not dependent on antigen processing and MHC class II molecules IA and IE were involved.

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© 1993 Plenum Press, New York

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Iqball, S., Bedford, P., Knight, S., Bhatt, R., Borriello, P. (1993). Dendritic Cells are Potent Antigen-Presenting Cells for Microbial Superantigen. In: Kamperdijk, E.W.A., Nieuwenhuis, P., Hoefsmit, E.C.M. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 329. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-2930-9_7

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  • DOI: https://doi.org/10.1007/978-1-4615-2930-9_7

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-6272-2

  • Online ISBN: 978-1-4615-2930-9

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