Modulation of MHC Class II Determinants on Rat Langerhans Cells During Short Term Culture

  • Ursula Neiß
  • Konrad Reske
  • Detlef Becker
  • Jürgen Knop
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)


Epidermal Langerhans cells (LC) are regarded as the most peripheral outpost of the immune system. They play a pivotal role during the onset of an immune response in the skin. One of the principal functions of LC is reflected in their extraordinary potency to present antigen to high activation requiring naive T cells.


Short Term Culture Invariant Chain Cell Surface Display Lymphoid Dendritic Cell Present Protein Antigen 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Ursula Neiß
    • 1
  • Konrad Reske
    • 1
  • Detlef Becker
    • 2
  • Jürgen Knop
    • 2
  1. 1.Institut für ImmunologieGutenberg UniversitätMainzGermany
  2. 2.Hautklinik der JohannesGutenberg UniversitätMainzGermany

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