Serum-Free Differentiation of Rat and Human Dendritic Cells, Accompanied by Acquisition of the Nuclear Lamins A/C as Differentiation Markers
It is generally accepted that tissue macrophages (Mφ) derive from a common bone marrow (BM) precursor. Clearly, it is the myeloid lineage that branches into the development of Mφ and granulocytes. For contrast, the exact origin of organ-specific dendritic cells (DC) is still doubtful. In vitro studies may help to solve this controversy. In this report we therefore present results gained from such investigations in our laboratory.
KeywordsDendritic Cell Accessory Cell Nuclear Lamins Myeloid Lineage Human Dendritic Cell
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