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The Role of Dendritic Cells as Co-Stimulators in Tolerance Induction

  • Michal Dabrowski
  • Mohammad A. A. Ibrahim
  • Benjamin M. Chain
  • David R. Katz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)

Abstract

In previous studies we have used an in vitro murine primary system to demonstrate that chemically modified antigen presenting cells (APC) were able to induce haplotype specific T cell hypo-responsiveness (1). This results confirmed a potentially important role of the APC in generation of peripheral T cell tolerance.

Keywords

Dendritic Cell Antigen Present Cell CD19 Positive Cell Cell Tolerance Potent Antigen Present Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Ibrahim M. A., 1991, J. Immunology, 147, 12, 4086–4093.Google Scholar
  2. 2.
    Mourad W., Geha R. S., Chatila T., 1990, J. Exp. Med., 172, 5, 1513–1516PubMedCrossRefGoogle Scholar
  3. 3.
    Jenkins M. K., 1987, Proc. Natl. Acad. Sci. USA, 84, 5409–5413.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Michal Dabrowski
    • 1
  • Mohammad A. A. Ibrahim
    • 1
  • Benjamin M. Chain
    • 1
  • David R. Katz
    • 1
  1. 1.Depts. of Histopathology, Immunology and BiologyUniversity College LondonLondonUK

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