Adhesion Molecules in Tonsil DC-T Cell Interactions

  • Derek N. J. Hart
  • Timothy C. R. Prickett
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)


The specific activation of a T lymphocyte depends on the interaction of its T cell receptor with the antigenic peptide - MHC complex on the surface of an antigen presenting cells (APC). In order for full primary T cell activation to occur the APC must provide essential additional co-stimulatory activity. 1 The ability to provide this “second signal” is a distinguishing feature of the specialist APC known as dendritic cells (DC) but the exact nature of this cellular property remains uncertain.2


Adhesion Molecule Dendritic Cell Migration Christchurch Hospital Dendritic Cell Preparation Immunoglobulin Gene Superfamily 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Derek N. J. Hart
    • 1
  • Timothy C. R. Prickett
    • 1
  1. 1.Haematology/Immunology Research GroupChristchurch School of Medicine Christchurch HospitalChristchurchNew Zealand

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