Adhesion Molecules in Tonsil DC-T Cell Interactions
The specific activation of a T lymphocyte depends on the interaction of its T cell receptor with the antigenic peptide - MHC complex on the surface of an antigen presenting cells (APC). In order for full primary T cell activation to occur the APC must provide essential additional co-stimulatory activity. 1 The ability to provide this “second signal” is a distinguishing feature of the specialist APC known as dendritic cells (DC) but the exact nature of this cellular property remains uncertain.2
KeywordsAdhesion Molecule Dendritic Cell Migration Christchurch Hospital Dendritic Cell Preparation Immunoglobulin Gene Superfamily
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