Skip to main content
SpringerLink
Log in

Cerebral Endothelial Mechanisms in Increased Permeability in Chronic Hypertension

  • Chapter
Frontiers in Cerebral Vascular Biology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 331))

Abstract

Our previous studies (4, 5) demonstrated that increased cerebrovascular permeability to protein in acute hypertension was associated with reduced activity of the endothelial plasma membrane adenosine triphosphatases (ATPases). This study was undertaken to determine when during the course of chronic hypertension a change in the activity of the plasma membrane calcium-activated ATPase (Ca2+-ATPase) and the ouabain-sensitive, K+ dependent p-nitrophenylphosphatase (Na+, K+ATPase) occurs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ando, T., Fujimoto, K., Mayahara, H., Miyajima, H., and Ogawa, H., A new one-step method for the histochemistry and cytochemistry of Ca2+-ATPase activity, Acta Histochem. Cytochem. 14: 705, 1981.

    Article  CAS  Google Scholar 

  2. Mayahara, H., Fujimoto, K., Ando, T., and Ogawa, K., A new one-step method for the cytochemical localization of ouabain-sensitive potassium-dependent p-nitrophenyl-phosphatase activity, Histochem. 67: 125, 1980.

    Article  CAS  Google Scholar 

  3. Nag, S., Cerebral cortical changes in chronic hypertension: Combined permeability and immunohistochemical studies, Acta Neuropathol. (Berl). 62: 178, 1984.

    Article  CAS  Google Scholar 

  4. Nag, S., Localisation of calcium-activated adcnosine-triphosphatase (Ca2+-ATPase) in intracerebral arterioles in acute hypertension, Acta Neuropathol. (Berl). 75: 547, 1988.

    Article  CAS  Google Scholar 

  5. Nag, S., Ultracytochemical localisation of Na+, K+-ATPase in cerebral endothelium in acute hypertension, A da Neuropathol. (Berl.) 80: 7, 1990.

    Article  CAS  Google Scholar 

  6. Nag, S., Protective effect of flunarizine on blood-brain barrier permeability alterations in acutely hypertensive rats, Stroke 22: 1265, 1991.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, Queen’s University, Kingston, Ontario, K7L 3N6, Canada

    Sukriti Nag

Authors
  1. Sukriti Nag
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Minnesota, Duluth, Minnesota, USA

    Lester R. Drewes

  2. The University of Michigan, Ann Arbor, Michigan, USA

    A. Lorris Betz

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer Science+Business Media New York

About this chapter

Cite this chapter

Nag, S. (1993). Cerebral Endothelial Mechanisms in Increased Permeability in Chronic Hypertension. In: Drewes, L.R., Betz, A.L. (eds) Frontiers in Cerebral Vascular Biology. Advances in Experimental Medicine and Biology, vol 331. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2920-0_41

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-2920-0_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6267-8

  • Online ISBN: 978-1-4615-2920-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation