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Components and Mechanisms Involved in Transport of Proteins into the Endoplasmic Reticulum

  • Chapter
Endoplasmic Reticulum

Part of the book series: Subcellular Biochemistry ((SCBI,volume 21))

Abstract

Every polypeptide has a unique intra- or extracellular location where it fulfills its function. In all eukaryotes, proteins are synthesized in a single compartment, i.e., the cytosol (excluding protein synthesis in mitochondria and chloroplasts). Noncytosolic proteins, therefore, have to be directed to different subcellular locations. In these cases, the sites of synthesis and functional location are separated by at least one biological membrane. Thus, mechanisms that ensure the specific transport of proteins across membranes must exist.

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Authors and Affiliations

  1. Zentrum Biochemie/Abteilung Biochemie II der Universität, D 37073, Göttingen, Germany

    Peter Klappa, Maria Zimmermann, Thomas Dierks & Richard Zimmermann

Authors
  1. Peter Klappa
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  2. Maria Zimmermann
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  3. Thomas Dierks
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  4. Richard Zimmermann
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Editor information

Editors and Affiliations

  1. CNR Center for Cytopharmacology, University of Milan, Milan, Italy

    N. Borgese

  2. Institute of Zoology, University of Mainz, Mainz, Germany

    J. R. Harris

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© 1993 Springer Science+Business Media New York

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Klappa, P., Zimmermann, M., Dierks, T., Zimmermann, R. (1993). Components and Mechanisms Involved in Transport of Proteins into the Endoplasmic Reticulum. In: Borgese, N., Harris, J.R. (eds) Endoplasmic Reticulum. Subcellular Biochemistry, vol 21. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2912-5_2

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  • DOI: https://doi.org/10.1007/978-1-4615-2912-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6263-0

  • Online ISBN: 978-1-4615-2912-5

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