Prevention of Cancer by Vitamin B3 (Nicotinamide and Nicotinic Acid)
Protease inhibitors (PIs) occur widely throughout plant and animal systems. Their role in preventing diseases in animals includes controlling blood clotting and contributing to the prevention of cancer. A workshop organized by the National Cancer Institute on “Protease Inhibitors as Cancer Chemopreventive Agents” concluded with the following recommendations for future research: (1) research and development of sources of PIs, (2) analysis of human foods for PI content, (3) evaluation of cancer incidence data in relation to PI content and characteristics in the diet of human populations, (4) animal studies on the efficacy of PIs in cancer prevention, and (5) studies on the mechanism of action of anticarcinogenic PIs (Troll et al., 1987).
KeywordsTumor Promotion Mouse Skin Chloromethyl Ketone Cancer Chemopreventive Agent Kunitz Soybean Trypsin Inhibitor
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