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The Epidemiologic Approach to the Study of Protease Inhibitors

  • Elizabeth Fontham
  • Pelayo Correa

Abstract

Protease inhibitors differ from other cancer-related dietary items in that the weight of the evidence of their protective effects is based on experimental and in vitro models rather than on studies in humans. For that reason the present comments focus on how to approach the issue from an epidemiologic point of view, with the purpose of establishing whether or not there is a causal association between protease inhibitors and human cancer. The multifactorial etiology of human cancer is a generally accepted scientific proposition. Protease inhibitors, therefore, may be just one of the factors in a complex interplay of carcinogenic and anticarcinogenic influences.

Keywords

Protease Inhibitor Green Leafy Vegetable Pancreatic Cancer Risk Protease Inhibitor Activity Cancer Chemopreventive Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Elizabeth Fontham
    • 1
  • Pelayo Correa
    • 1
  1. 1.Department of PathologyLouisiana State University Medical CenterNew OrleansUSA

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