Abstract
Although previous studies have demonstrated that acidosis increases bone blood flow, it is unclear whether this is due to a direct effect of hydrogen ion concentration ([H+]) on bone blood vessels or a central effect on vasoregulatory mechanisms. It is also unclear how sensitive bone blood vessels are to changes in [H+] and whether the magnitude of pH changes experienced in physiological and pathological situations are sufficient to influence bone blood flow. This study has investigated the direct effects of [H+] on long bone vascular resistance.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Plenum Press, New York
About this chapter
Cite this chapter
Davis, T.R.C., Wood, M.B. (1993). The Direct Effects of Acidosis and Alkalosis on Long Bone Vascular Resistance. In: Schoutens, A., Arlet, J., Gardeniers, J.W.M., Hughes, S.P.F. (eds) Bone Circulation and Vascularization in Normal and Pathological Conditions. NATO ASI Series, vol 247. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2838-8_7
Download citation
DOI: https://doi.org/10.1007/978-1-4615-2838-8_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-306-44523-1
Online ISBN: 978-1-4615-2838-8
eBook Packages: Springer Book Archive