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Actin pp 183–189Cite as

Actin Filaments and the Spatial Positioning of mRNAS

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 358))

Abstract

Filamentous actin has been shown to play a major role in the control of mRNA expression. Previous work emphasized RNA-cytoskeletal interactions using biochemical fractionation. More recently, in situ hybridization at the light microscopic and ultrastructural levels has shown that actin, in particular, is directly associated with mRNAs. It is proposed that these interactions play a major regulatory role in how the mRNA is spatially sequestered within the cytoplasm and provide a mechanism for its regulation (Singer, 1992).

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© 1994 Springer Science+Business Media New York

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Bassell, G.J. et al. (1994). Actin Filaments and the Spatial Positioning of mRNAS. In: Estes, J.E., Higgins, P.J. (eds) Actin. Advances in Experimental Medicine and Biology, vol 358. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2578-3_17

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  • DOI: https://doi.org/10.1007/978-1-4615-2578-3_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6102-2

  • Online ISBN: 978-1-4615-2578-3

  • eBook Packages: Springer Book Archive

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