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Biochemical Aspects of Presynaptic Function

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Bioelectrochemistry IV

Part of the book series: NATO ASI Series ((NSSA,volume 267))

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Abstract

Neurons are highly polarized cells in which several compartments, such as cell body, dendrites, axons and nerve endings can be distinguished. The proteins of the presynaptic nerve terminal are synthesized in the cell body, from where they are targeted down the axon to their site of action. The sorting signal is not known, and there is some debate as to whether membrane proteins of synaptic vesicles leave the cell body assembled in mature synaptic vesicles or in pleiomorphic membranous structures from which synaptic vesicles are derived at later stages (De Camilli and Jahn, [1]).

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Author information

Authors and Affiliations

  1. “Bruno Ceccarelli” Centre, Department of Medical Pharmacology, CNR Center of Cytopharmacology and S. Raffaele Institute, University of Milan, Italy

    Flavia Valtorta & Numa Iezzi

  2. Institute of Human Physiology, University of Modena, Italy

    Fabio Benfenati

  3. Friedrich-Miescher Laboratorium der Max-Planck Gesellschaft, Tübingen, Germany

    Martin Bähler

Authors
  1. Flavia Valtorta
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  2. Fabio Benfenati
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  3. Numa Iezzi
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  4. Martin Bähler
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Editor information

Editors and Affiliations

  1. University of Bologna, Bologna, Italy

    Bruno Andrea Melandri

  2. Late of Instituto Superiore di Sanita, Rome, Italy

    Giulio Milazzo

  3. Columbia University, New York, New York, USA

    Martin Blank

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© 1994 Plenum Press, New York

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Valtorta, F., Benfenati, F., Iezzi, N., Bähler, M. (1994). Biochemical Aspects of Presynaptic Function. In: Melandri, B.A., Milazzo, G., Blank, M. (eds) Bioelectrochemistry IV. NATO ASI Series, vol 267. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2576-9_5

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  • DOI: https://doi.org/10.1007/978-1-4615-2576-9_5

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  • Online ISBN: 978-1-4615-2576-9

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