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Electrotonic Coupling between Carotid Body Glomus Cells

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Book cover Arterial Chemoreceptors

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 360))

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Abstract

The carotid body detects chemical changes in the blood such as PO2, PCO2 and pH, and generates afferent discharges in the carotid nerve. During stimulation, the glomus cells release endogenous substances (ACh, catecholamines, and neuropeptides) toward the carotid nerve terminals. To understand how secretion occurs, we have studied the electric connections between glomus cells at rest and during activity elicited by ‘natural’ stimuli, or the transmitters (Monti-Bloch et al., 1990, 1993). In other secretory organs, adjoining cells are electrically coupled and they uncouple (fully or partially) during secretion (for refs. see Bennett & Spray, 1985; Hertzberg & Johnson, 1988; Bennett et al., 1991).

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© 1994 Springer Science+Business Media New York

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Monti-Bloch, L., Abudara, V., Eyzaguirre, C. (1994). Electrotonic Coupling between Carotid Body Glomus Cells. In: O’Regan, R.G., Nolan, P., McQueen, D.S., Paterson, D.J. (eds) Arterial Chemoreceptors. Advances in Experimental Medicine and Biology, vol 360. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2572-1_15

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  • DOI: https://doi.org/10.1007/978-1-4615-2572-1_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6099-5

  • Online ISBN: 978-1-4615-2572-1

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