Urolithiasis 2 pp 275-279 | Cite as

Evidence that Uric Acid Abolishes Citrate-Mediated Inhibition of Calcium Oxalate Monohydrate Agglomeration in Vitro

  • S. M. Volta
  • E. E. Fradinger
  • C. E. Bogado
  • J. R. Zanchetta

Abstract

Calcium oxalate monohydrate (COM) crystal growth and agglomeration in urine are modulated by a complex set of chemical and physical properties of the medium. In such a chemically complex milieu, where many effects of these properties can mask each other, it is virtually impossible to identify and/or quantify them separately. However, considerable advantage can be gained in the understanding of the mechanisms involved by testing the effects of some of the species present in urine in isolation, or in combination with only a small number of other urinary constituents.

Keywords

Crystallization Citrate Dimethyl Oxalate Agglomeration 

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • S. M. Volta
    • 1
  • E. E. Fradinger
    • 1
  • C. E. Bogado
    • 1
  • J. R. Zanchetta
    • 1
  1. 1.Instituto de Investigaciones MetabolicasBuenos AiresArgentina

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