Oral Cimetidinein Humans - Evidence For Urine Acidification and Inhibition of Calcium Oxalate Crystallization
Medication of subgroups of idiopathic calcium urolithiasis often aims at reducing an alkaline or insufficiently acidic urinary pH. Since (exogenous) acid loading is effective but instantly attacks the body’s buffer reservoirs, we tested the hypothesis that inhibition of postprandial gastric proton release into the gastric lumen may lead to proton diversion to kidney via blood, and to subsequent excretion via urine.
KeywordsPrimary Hyperparathyroidism Calcium Oxalate Acid Loading Stone Patient Subsequent Excretion
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