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Urolithiasis 2 pp 137-138 | Cite as

Erythrocyte Band 3 Protein Phosphorylation Modulates Anion Transport in Nephrolithiasic Patients

  • B. Baggio
  • L. Bordin
  • G. Gambaro
  • M. Vincenti
  • M. Nassuato
  • G. Clari

Abstract

Higher oxalate1, and urate2 transmembrane self-exchange rates, and a faster endogenous phosphorylation of band 3 protein3, the anion carrier, were found in red cells from idiopathic calcium-oxalate renal stone formers. That these two cellular-abnormalities might be linked is an attractive hypothesis, but it is still debated whether anion transport modulation involves the phosphorylation of band 3 and other membrane proteins. To investigate this problem further, we studied the effect of agents known to interfere with membrane protein phosphorylation on anion transport.

Keywords

Anion Transport Phorbol Myristate Acetate Anion Carrier Calcium Nephrolithiasis NEPHROLITHIASIC Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    B Baggio, G Gambaro, F Marchini et al, An inheritable anomaly of red blood cells in idiopathic calcium oxalate nephrolithiasis correctable with diuretics. New Eng J Med 314: 599 (1986).PubMedCrossRefGoogle Scholar
  2. 2.
    G Gambaro, F Marchini, M Vincenti et al, Erythrocyte urate self-exchange in idiopathic calcium nephrolithiasis. In this volume.Google Scholar
  3. 3.
    B Baggio, G Clari, G Marzaro et al, Altered red blood cell membrane protein phosphorylation in idiopathic calcium oxalate nephrolithiasis. IRCS Med Sci 14: 368 (1986).Google Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • B. Baggio
    • 1
  • L. Bordin
    • 1
  • G. Gambaro
    • 1
  • M. Vincenti
    • 1
  • M. Nassuato
    • 1
  • G. Clari
    • 1
  1. 1.Institutes of Internal Medicine and BiochemistryUniversity of PadovaItaly

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