Silicate calculi are frequent in herbivorous animals1 and small amounts of silicate are regularly present in human calculi2. Recently it has been reported that the presence of polymerized silicate will decrease the concentrations of calcium and phosphorus required for mineralization of tissues in vitro 3. Previously the author has reported that the addition of small amounts of polymerized silicate to urine of normal subjects, 5 to 20 mg per 100 mL of urine, will overcome the effect of inhibitors of mineralization in such urine4.
KeywordsRenal Stone Calculus Formation Silicate Content Water Supply Paper Water Silicate
- 4.WC Thomas Jr, Inhibitors of mineralization and renal stones, in: “Renal Stone Research Symposium”, A Hodgkinson and BEC Nordin, eds, J & A Churchill, Ltd, London (1969).Google Scholar
- 6.US Geological Survey. Water Supply Papers 1299 and 1300, U. S. Government Printing Office, Washington, DC (1954).Google Scholar