Urolithiasis 2 pp 373-374 | Cite as

Urinary Silicate in Calculous Patients

  • W. C. Thomas


Silicate calculi are frequent in herbivorous animals1 and small amounts of silicate are regularly present in human calculi2. Recently it has been reported that the presence of polymerized silicate will decrease the concentrations of calcium and phosphorus required for mineralization of tissues in vitro 3. Previously the author has reported that the addition of small amounts of polymerized silicate to urine of normal subjects, 5 to 20 mg per 100 mL of urine, will overcome the effect of inhibitors of mineralization in such urine4.


Renal Stone Calculus Formation Silicate Content Water Supply Paper Water Silicate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    CB Bailey, Silica metabolism and silica urolithiasis in ruminants: A review, Can J Animal Sci 61: 219 (1981).CrossRefGoogle Scholar
  2. 2.
    AA Levinson, N Miloslav, M Davidman, EL Prien Sr, EL Prien Jr, and RG Stevenson, Trace elements in kidney stones from three areas in the United States, Invest Urol 15: 270 (1978).PubMedGoogle Scholar
  3. 3.
    A Anasuya and BS Marasingo Rao, Effect of fluoride, silicon and magnesium on the mineralizing capacity of an inorganic medium and stone formers urine tested by a modified in vitro method, Biochem Med 30: 146 (1983).PubMedCrossRefGoogle Scholar
  4. 4.
    WC Thomas Jr, Inhibitors of mineralization and renal stones, in: “Renal Stone Research Symposium”, A Hodgkinson and BEC Nordin, eds, J & A Churchill, Ltd, London (1969).Google Scholar
  5. 5.
    EJ King and BD Stacy, The colorimetric determination of silicon in the micro-analysis of biological material and mineral dusts, Analyst 80: 441 (1955).CrossRefGoogle Scholar
  6. 6.
    US Geological Survey. Water Supply Papers 1299 and 1300, U. S. Government Printing Office, Washington, DC (1954).Google Scholar
  7. 7.
    R Sierakowski, B Finlayson and R Landes, Stone incidence as related to water hardness in different geographical regions of the United States, Urol Res 7: 157 (1979).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • W. C. Thomas
    • 1
  1. 1.University of Florida College of Medicine and VA Medical CenterGainesvilleUSA

Personalised recommendations