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Progress in Iron Research pp 165–171Cite as

Intracellular Iron

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 356))

Abstract

Iron enters the cell bound to its transport protein, transferrin, from which it is freed. It then traverses the cell’s cytosol and finds its way into protoporphyrin, iron sulfur centers and ferritin’s core. The means by which these transfers are effected is not known. Disparate observations have been rationalized as follows: that the iron mixes in a “chelatable” pool comprised of low MW ligands; that these mediate the intracellular iron transfers. However, the ligands in the low MW, chelatable pool have not been identified.

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Author information

Authors and Affiliations

  1. Albert Einstein College of Medicine, Bronx, NY, 10461, USA

    Simeon Pollack

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  1. Simeon Pollack
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Editor information

Editors and Affiliations

  1. Shaare Zedek Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel

    Chaim Hershko

  2. The Hebrew University Hadassah Medical School, Jerusalem, Israel

    Abraham M. Konijn

  3. Albert Einstein College of Medicine, Bronx, New York, USA

    Philip Aisen

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© 1994 Springer Science+Business Media New York

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Pollack, S. (1994). Intracellular Iron. In: Hershko, C., Konijn, A.M., Aisen, P. (eds) Progress in Iron Research. Advances in Experimental Medicine and Biology, vol 356. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2554-7_19

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  • DOI: https://doi.org/10.1007/978-1-4615-2554-7_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6090-2

  • Online ISBN: 978-1-4615-2554-7

  • eBook Packages: Springer Book Archive

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