Abstract
All living organisms require several different transition metal ions to develop, grow, and function as designed. Since many of these metal ions, like copper, zinc and iron are so reactive that the biochemical reactions dependent on these essential elements typically involve the formation of specific protein-metal ion complexes or chelates. Indeed, the absorption, transport, cellular accumulation, and steady-state molecular distribution of these transition metal ions within and between intracellular compartments would appear to be determined, in part, by a series of directional metal ion transfer events between macromolecules.
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Yip, TT., Hutchens, T.W. (1994). Interaction of Lactoferrin with Sequestered Transition Metal Ions. In: Hutchens, T.W., Rumball, S.V., Lönnerdal, B. (eds) Lactoferrin. Advances in, Experimental Medicine and Biology, vol 357. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2548-6_6
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DOI: https://doi.org/10.1007/978-1-4615-2548-6_6
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