• C. Diebler
  • O. Dulac
Part of the NATO ASI Series book series (NSSA, volume 264)


Hemimegalencephaly is a variant of cortical dysplasia involving the whole hemisphere (Robain et al., 1988). There is no clear border between the two types of malformation because from one to several lobes can be involved whereas the rest of the hemisphere is spared. The histological findings are similar in both types of malformation and consist of disappearance of cortical lamination and presence of giant neurons, giant glial cells with Rosenthal’s fibres and occasionally calcifications. The white matter underlying the abnormal cortex is also involved.


Infantile Spasm Cortical Dysplasia Suppression Burst Cortical Lamination Giant Neuron 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • C. Diebler
    • 1
  • O. Dulac
    • 2
  1. 1.Centre Medico-Chirurgical FochSuresnesFrance
  2. 2.Hôpital Saint-Vincent-de-PaulParisFrance

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