The Significance of T2 Changes in the Hippocampus

  • P. Tofts
Part of the NATO ASI Series book series (NSSA, volume 264)


Relaxation times T1 and T2 can be measured accurately and reproducibly in the brain (Tofts and Du Boulay, 1990), enabling white matter in different disease groups to be differentiated (Miller et al., 1989). However, scanner performance can degrade both accuracy and reproducibility, and the pathological cause of changes in relaxation times has yet to be established with certainty.


Relaxation Time White Matter Central Nervous System Disease Magnetisation Transfer Nuclear Magnetic Resonance Relaxation 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • P. Tofts
    • 1
  1. 1.Institute of NeurologyLondonUK

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