Abstract
An industrial process for the electrochemical synthesis of DL-Homocysteine from DL-Homocystine is described. DL-Homocysteine is a key intermediate for the synthesis of Citiolone (a powerful agent used to treat bronchitis and nasal catarrh). The work starts with a fundamental study, the voltammetric behaviour of DL-Homocystine, followed by a laboratory and pilot plant study and finishes with the development of an industrial process (30 tons/year of DL-Homocistine electroreduced). The method avoids the use of hazardous and polluting reductants such as Zn/H+. The figures of merit are a material yield of 95%, production over 200kg/m2day and a energy cost less than 2 kWh/kg.
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© 1995 Springer Science+Business Media New York
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Sánchez-Cano, G., Montiel, V., García, V., Aldaz, A., Elías, E. (1995). From Voltammetry to Industrial Plant: Electrochemical Synthesis of DL-Homocysteine from DL-Homocystine — An Example of Scale-Up. In: Lapicque, F., Storck, A., Wragg, A.A. (eds) Electrochemical Engineering and Energy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2514-1_16
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DOI: https://doi.org/10.1007/978-1-4615-2514-1_16
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