Effect of Conjugated Linoleic Acid on Carcinogenesis

  • Joseph A. Scimeca
  • Henry J. Thompson
  • Clement Ip
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 364)


Conjugated linoleic acid (CLA) refers to a mixture of positional and geometric isomers of linoleic acid. The two double bonds in CLA are primarily in positions 9 and 11, or 10 and 12, along the carbon chain, thus giving rise to the designation of a conjugated diene. Each of the double bonds can be in the cis or {trans} configuration, and hence eight isomers are formed from the isomerization of linoleic acid.


Linoleic Acid Conjugate Linoleic Acid Dietary Conjugate Linoleic Acid Conjugate Linoleic Acid Content Cytochrome P450 Isozyme 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Joseph A. Scimeca
    • 1
  • Henry J. Thompson
    • 2
  • Clement Ip
    • 3
  1. 1.Nutrition DepartmentKraft General FoodsGlenviewUSA
  2. 2.Laboratory of Nutrition ResearchAMC Cancer Research CenterDenverCanada
  3. 3.Department of Surgical OncologyRoswell Park Cancer InstituteBuffaloUSA

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