Selection of Anti-Arsonate Idiotype (CRIA) in A/J Mice by the Immune Network

  • Maryse Brait
  • Marion Ryelandt
  • Jamila Ismaili
  • Robert Miller
  • Georgette Vansantem
  • Roy Riblet
  • Jacques Urbain
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 355)

Abstract

A/J mice immunized against arsonate (ARS) coupled to hemocyanin (KLH) synthesize a cross reactive idiotype named CRIA (Kuettner et al., 1972). This idiotype is encoded by a single combination of genes called the canonical combination which is constituted of one VH gene (VHIdCR11), one D segment (DFL16.1), one JH segment (JH2), one VK gene (VKIdCR) and one JK segment (JK1).

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Maryse Brait
    • 1
  • Marion Ryelandt
    • 1
  • Jamila Ismaili
    • 1
  • Robert Miller
    • 2
  • Georgette Vansantem
    • 1
  • Roy Riblet
    • 2
  • Jacques Urbain
    • 1
  1. 1.Laboratoire de Physiologie AnimaleUniversité Libre de BruxellesBelgium
  2. 2.Medical Biology InstituteLa JollaUSA

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