Abstract
GISCAD was established in July 1990, following the positive experience of the Medical Therapy Group of FONCAD (Italian Task Force against Digestive Tract Cancer).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
R. Labianca, G. Pancera, E. Aitini, S. Barni, A. Beretta, G.D. Beretta, B. Cesana, G. Cornelia, L. Cozzaglio, M. Cristoni, P. Spagnolli, L. Frontini, O. Gottardi, G. Martignoni, R. Scapaticci, F. Smerieri, M. Vinci, A. Zadro, A. Zaniboni, and G. Luporini: “Folinic Acid + 5-Fluorouracil (5FU) Versus Equidose 5FU in Advanced Colorectal Cancer. Phase III Study of GISCAD (Italian Group for the Study of Digestive Tract Cancer”. Ann. Oncol. 2: 673–679 (1991).
P. Piedbois, M. Buyse, Y. Rustum, D. Machover, C. Erlichman, R.N. Carlson, F. Valone, R. Labianca, J.H. Doroshow and N. Petrelli: “Modulation of Fluorouracil by Leucovorin in Patients with Advanced Colorectal Cancer: Evidence in Terms of Response Rate”. J. Clin. Oncol. 10: 896–903 (1992).
S. Nadler and P.M. Niernik: “Clinical Update on the Role of Fluorouracil and Recombinant Interferon-alpha 2a in the Treatment of Colorectal Carcinoma”. Semin. Oncol. 17: 16–21 (1990).
R. Labianca, G. Pancera, L. Tedeschi, G. Dallavalle, and G. Luporini: “High-dose Alpha 2b Interferon + Folinic Acid in the Modulation of 5-Fluorouracil. A Phase II Study in Advanced Colorectal Cancer with Evidence of an Unfavorable Cost/Benefit Ratio”. Tumori, 78: 32–34 (1992).
C. Allegra: “Clinical Drug Resistence”. ASCO Editorial Booklet, 197–229 (1990).
M.A. Poon, M.J. O’Connell and H.S. Wieand: Biochemical Modulation of Fluorouracil with Leucovorin. Confirmatory Evidence of Improved Therapeutic Efficacy in Advanced Colorectal Cancer”. J. Clin. Oncol. 9: 1967–1972 (1991).
J. Gerstner, M.J. O’Connell, H.S. and H.S. Nieand: “A Prospectively Randomized Clinical Trial Comparing 5FU Combined with Either High or Low Dose Leucovorin for the Treatment of Advanced Colorectal Cancer”. Proc. ASCO 404 (1991).
G. Pancera, R. Labianca, Y.M. Rustum, M. Clerici and G. Luporini: “Biochemical Modulation of 5-Fluorouracil with 4-hours Infusion of Folinic Acid: A Pilot Study in Advanced Colorectal Cancer”. Proc. ASCO 494 (1991).
G. Pancera, R. Labianca, S. Samori, G. Mortara, M. Pirovano, G. Giaccon, A.C. Luporini, D. Tabiadon, G. Dallavalle and G. Luporini: “Chemioterapia Locoregionale e Sistemica nelle Metastasi Epatiche da Carcinoma del Colon-Retto”. X Riunione AIOM, Pordenone, 4–7 Novembre (1992).
J.L. Grem, N. McAtee, R.F. Murphy: “A Pilot Study of Interferon Alpha 2a in Combination with Fluorouracil Plus High-Dose Leucovorin in Metastatic Gastrointestinal Carcinoma”. J. Clin. Oncol. 9: 1811–1917 (1991).
S. Cascinu, A. Fedeli, S. Luzi Fedeli and G. Catalano: “Double Biochemical Modulation of 5-Fluorouracil by Leucovorin and Cyclic Low-dose Interferon Alpha-2b in Advanced Colorectal Cancer Patients”. Ann. Oncol. 3: 489–491, (1992).
D. Machover, X. Grison, E. Goldschmidt, J. Zittoun, J. Plotz and G. Metzger: “Fluorouracil Combined with the Pure (65) Stereoisomer of Folinic Acid in High-dose for Treatment of Patients with Advanced Colorectal Carcinoma: A Phase I-II Study”. J.N.C. I. 5: 321–327, 1992.
G. Pancera, D. Nitti, D. Civalleri, S. Marsoni, R. Labianca, M. Lise, V. Bachi and G. Luporini: “A Retrospective Analyis of 119 Patients with Resected Metastases from Colorectal Cancer: Is There a Role for Adjuvant Chemotherapy?”. Proc. ASCO 524, 1992.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer Science+Business Media New York
About this chapter
Cite this chapter
Labianca, R. et al. (1993). Biochemical Modulation of Fluoropyrimidines: the “Giscad” Studies. In: Rustum, Y.M. (eds) Novel Approaches to Selective Treatments of Human Solid Tumors. Advances in Experimental Medicine and Biology, vol 339. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2488-5_23
Download citation
DOI: https://doi.org/10.1007/978-1-4615-2488-5_23
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6060-5
Online ISBN: 978-1-4615-2488-5
eBook Packages: Springer Book Archive