Skip to main content
SpringerLink
Log in
Book cover

Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy pp 45–56Cite as

Nutritional Considerations in Patients with Hepatic Failure

  • Chapter

  • 74 Accesses

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 341))

Abstract

The evolution of the patients affected by chronic hepatopathy is a problem which results in a high percentage of surgical interventions. Portal hypertension leads to one of the most serious dangers for the lives of these patients: upper digestive hemorrhage with its hemodynamic and metabolic sequels. The situation is dramatized by an ever — increasing circumstance: the ethylic origen of the hepatic lesion strikes in increasingly younger ages, or in the best of cases, in the middle stages of life. It must be pointed out that the consumption of pure ethanol “per capita” annually in Spain is 13 liters. The consumption of beer has risen to 50 liters; wine consumption remains at 60 liters and spirits of 40° at 7.5 liters per capita and year [1].

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Caballeria, J. and Pares, A., Alcohol e hígado en enfermedades digestivas. Ediciones CEA, Madrid, 1990, pp. 2103–2117.

    Google Scholar 

  2. Pomar, M.J., Bruguera, M., Caballeria, J., and Rodes, J., Malnutrition calórico-proteíca en pacientes hepáticos hospitalizados. Gastroenterología y Hepatología, Vol. 10, n° 9, 1987, pp. 434–440.

    Google Scholar 

  3. Leevy, C.M., Baker, H., Hove, W., et al., P-complex vitamins in liver disease of the alcoholic. Am. Jour. of Clin. Nutr. 16, 1965, pp. 339–346.

    CAS  Google Scholar 

  4. Mezey, E., Liver disease and nutrition. Gastroenterology, 74, 1978, pp. 770–783.

    PubMed  CAS  Google Scholar 

  5. Thompson, G.R., Barrowman, J., Gutierrez, L., et al. Actions of Neomycin on the intraluminal phase of lipid absorption. J. Clin. Invest., 50, 1971, pp. 319–323.

    Article  PubMed  CAS  Google Scholar 

  6. Hashim, S.A., Bergen, S.S., Van Itallie, T.B., Experimental esteatorreha induced in man by bill [sic] acid sequestrant. Proc. Soc. Exp. Biol. Med. 106: 1961, pp. 173–175.

    PubMed  CAS  Google Scholar 

  7. Collins, j.R., Lacy, W.W., and Stiel, J.N. et al. Glucose intolerance and insulin resistence in patients with liver disease. II A Study of aetiologic factors and evaluation of insulin actions. Arch. Inter. Med. 127, 1970, pp. 608–614.

    Article  Google Scholar 

  8. Dupre, J., Curtis, J.D., Unger, R.H. et al. Effects of secretin, pancreozymin or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man.

    Google Scholar 

  9. Goldstein, J.L., Kita, T., and Brown, M.S., Defective lipoprotein receptors and atherosclerosis, lessons from an animal counterpart of Familial Hipercolesterolemia.

    Google Scholar 

  10. Brown, M.S., Kovanen, P.T. and Goldstein, J.L., Regulation of plasma cholesterol by lipoprotein. Science 212, 1981, pp. 628–635.

    Article  PubMed  CAS  Google Scholar 

  11. Hoeg, J.M., Demosky, S.J., and Greff, R.E., Distinct hepatic receptors for low density lipoprotein and apolipoprotein E in humans. Science 277, 1985, pp. 759–761.

    Article  Google Scholar 

  12. Manley, R.W. and Interarity, J.L., Lipoprotein receptors and cholesterol homeostasis. Biochem. Biophys. Acta 737, 1983, pp. 197–222.

    Article  Google Scholar 

  13. Haussinger, D., Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Am. J. Biochem. 133, 1983, pp. 269–275.

    CAS  Google Scholar 

  14. Hepner, G.W., Roginsky, M. and Moo, H.F., Abnormal vitamin D metabolism in patient with cirrhosis. Am. J. dis. 21, 1976, pp. 527–532.

    Article  CAS  Google Scholar 

  15. Fennelli J., Frank, O., Baker, et al., Red blood cell transketolase activity in malnourished alcoholics with cirrhosis. Am. Jour. Clin. Nutr. 20, 1967, pp. 946–949.

    Google Scholar 

  16. Fischer, J.E. and Baldessarini, R.J., False neurotransmitters and hepatic failure. Lancet 2, 1971, pp. 75–85.

    Article  PubMed  CAS  Google Scholar 

  17. Baldessarini, R.J. and Fischer, J.E., Serotonin metabolism in rat brain after judicial diversion of the portal venoces circulation. Nature 245, 1973, pp. 25–35.

    Article  CAS  Google Scholar 

  18. Harnes, H.J., Jepson, B., Ziparo, V., Fischer, J.E., Hyperammonemia plasma aminoacid imbalance, and blood brain aminoacid transport: a unified theory of portal. Lancet ii, 1979, pp. 772.

    Google Scholar 

  19. Mans, A., et al., Early establishment of cerebral disfunction after portacaval shunting. Am. Physiol. Soc, 1990, 0193–1849, pp. E104-E106.

    Google Scholar 

  20. Cerra, F.B., Cheung, N.K., Fischer, J.E. et al., A multicenter trial of branched chain enriched aminoacid infusiores (F080) in hepatic encephalopathy. Hepatalolgy Z., 1982, pp. 699.

    Google Scholar 

  21. Rossi-Fanelli, F., Cascino, A., Cangiano, C., Branched chain aminoacids in the management of hepatic encephalopathy. J. Clin. Gastroenterol. Z., 1987, pp. 44–46.

    Google Scholar 

  22. Warren, K.S., Shenker, S., Effect of and inhibitor of Glutamine Synthesis on Ammonia toxicity and metabolism. J. Lab. Clin. Med. 64, 1964, pp. 442.

    PubMed  CAS  Google Scholar 

  23. Silk, D.B.A., Parenteral nutrition in patients with liver disease. Journal of Hepatology 7, 1988, pp. 269–277.

    Article  PubMed  CAS  Google Scholar 

  24. Sastre, A., et al., Nutrición en la insuficiencia hepática. In Nutritión artificial en el paciente grave. Edit. Doyma. Barcelona, 1989, pp. 45–47.

    Google Scholar 

  25. Reynolds, J.V., Daly, J.M., et al., Immunomodulatory mechanisms of arginine. Surgery, 104, n° 2, 1988, pp. 143–151.

    Google Scholar 

  26. Barbul, A., Lazarou, S.A., Efron, D., et al., Arginine entrances wound healing and lynphocyte immune responses in humans. Surgery, Vol. 108, n° 2, 1990, pp. 331–337.

    PubMed  CAS  Google Scholar 

  27. Carda, P., Saastre, A., La Roche, F., Morales, V. and Marcos, J. M. Correction of Aminoacid imbalance in Postoperative portalsystemic Shunts. Infusiontherapie 12, 1985, pp. 251–253.

    CAS  Google Scholar 

  28. Garcia Almansa, A., et al., Nutrición y hepatopatía, In Introductión a la Nutrición Clínica hospitalaria. P.P. Garcia Luna, Edit. SAS, 1990, pp. 251–260.

    Google Scholar 

  29. Muñoz, S.J., Nutritional therapies in liver disease. Seminars in liver disease, Vol. II, n° 4, 1991, pp. 278–291.

    Article  Google Scholar 

  30. Mans, Anke M. et al., Early establishment of cerebral dysfunction after portacaval shunting. Amer. Physiological Soc., 1990, 0193-1849/90, pp. E104–E109.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dpto. de Cirugia General y Digestiva, Hospital “Ramón y Cajal”, Unidad de Nutrición Clínica y Dietética, Madrid, Spain

    A. Sastre Gallego, E. Morejón Bootello & P. Carda Abella

Authors
  1. A. Sastre Gallego
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Morejón Bootello
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Carda Abella
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Instituto de Investigaciones Citologicas, Valencia, Spain

    Santiago Grisolía  & Vicente Felipo  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer Science+Business Media New York

About this chapter

Cite this chapter

Gallego, A.S., Bootello, E.M., Abella, P.C. (1993). Nutritional Considerations in Patients with Hepatic Failure. In: Grisolía, S., Felipo, V. (eds) Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy. Advances in Experimental Medicine and Biology, vol 341. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2484-7_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-2484-7_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6058-2

  • Online ISBN: 978-1-4615-2484-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation