Oxygenation Status of Rhabdomyosarcoma Spheroids with Different Stages of Differentiation

  • H. Stier
  • U. Karbach
  • C.-D. Gerharz
  • H. Gabbert
  • W. Mueller-Klieser
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 345)

Abstract

Multicellular tumor spheroids with regional heterogeneities of proliferation and substrate concentrations have been investigated recently to study the biological properties of small tumor nodules prior to onset of vascularization (for reviews see: Mueller-Klieser, 1987; Sutherland, 1988).

Keywords

Convection Lactate Shrinkage Penicillin Sarcoma 

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • H. Stier
    • 1
  • U. Karbach
    • 1
  • C.-D. Gerharz
    • 1
  • H. Gabbert
    • 1
  • W. Mueller-Klieser
    • 1
  1. 1.Institute of Physiology and PathophysiologyUniversity of MainzMainzGermany

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