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Radiation Induced Chromosomal Damage to Lymphocytes in Usual 99mTc-HMPAO Leukocyte Preparations

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Radiolabeled Blood Elements

Part of the book series: NATO ASI Series ((NSSA,volume 262))

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Abstract

99mTc-HMPAO leukocyte labeling (LL) was considered to result in a substantially “pure” granulocyte tagging because of the different elution rate of radioactivity from the blood elements.

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References

  1. De Labriolle-Vaylet C, Colas Linhart N, Petiet A, Bok B. Morphological and functional status of leukocytes labelled with 99mTc-HMPAO. In: Radiolabelled Cellular Blood Elements, Sinzinger H and Thakur ML Edts. Wiley-Liss New York 1990; 119–129

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  2. Thieens HMA, Vral AM, Van Haelst JP et al. Lymphocyte labeling with technetium-99m-HMPAO: a radiotoxicity study using the micronucleus assay. J Nucl Med;, 33: 1167–1174 (1992).

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  3. Thakur ML, McAfee JG. The significance of chromosomal aberrations in Indium-111-labeled lymphocytes. J Nucl Med;, 25: 922–927 (1984).

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Author information

Authors and Affiliations

  1. Dept. of Nuclear Medicine, Ospedale Maggiore, Bologna, Italy

    A. Furno

  2. Dept. of Clinical Pathology, Ospedale Maggiore, Bologna, Italy

    R. Gallo & M. Gambetti

  3. Dept. of Immunohaematology, Ospedale Maggiore, Bologna, Italy

    C. Basile

Authors
  1. A. Furno
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  2. R. Gallo
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  3. M. Gambetti
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  4. C. Basile
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Editor information

Editors and Affiliations

  1. Department of Nuclear Medicine, CSUB Hospital “Princeps d’Espanya”, Barcelona, Spain

    J. Martin-Comin

  2. Division of Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

    M. L. Thakur

  3. Department of Nuclear Medicine, Hospital Clinic, Barcelona, Spain

    C. Piera

  4. Department of Nuclear Medicine, CSUB Hospital “Princeps d’Espanya”, Barcelona, Spain

    M. Roca

  5. Department of Nuclear Medicine, Hospital Clinic, Barcelona, Spain

    F. Lomeña

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© 1994 Springer Science+Business Media New York

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Furno, A., Gallo, R., Gambetti, M., Basile, C. (1994). Radiation Induced Chromosomal Damage to Lymphocytes in Usual 99mTc-HMPAO Leukocyte Preparations. In: Martin-Comin, J., Thakur, M.L., Piera, C., Roca, M., Lomeña, F. (eds) Radiolabeled Blood Elements. NATO ASI Series, vol 262. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2462-5_26

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  • DOI: https://doi.org/10.1007/978-1-4615-2462-5_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6048-3

  • Online ISBN: 978-1-4615-2462-5

  • eBook Packages: Springer Book Archive

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