Abstract
There is a growing evidence that immunological. system is involved in surveillance against HPV-associated neoplasia.1 The immune mechanisms responsible for eradication of HPV-induced tumors may include direct participation of natural. killer (NK) cells,2 activated macrophages,3 and cytotoxic T lymphocytes.4Furthermore, growth and dissemination of potentially malignant lesions may be under control of locally released im-munoregulatory anti-tumor cytokines including interferons,5 inter Ieukin-6, transforming growth factor-β,7 as well as tumor necrosis factor-α (TNF-α).8
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Malejczyk, J. et al. (1994). Release of Soluble Tumor Necrosis Factor-α (TNF-α) Receptor by HPV-Associated Neoplastic Cells. In: Stanley, M.A. (eds) Immunology of Human Papillomaviruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2449-6_49
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DOI: https://doi.org/10.1007/978-1-4615-2449-6_49
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