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Immunogenetic Study of Women with HPV Related Cancer of the Uterine Cervix

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Immunology of Human Papillomaviruses

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Abstract

It has been suggested that women carrying the HLA-DQ3 antigen are at increased risk of developing cervical. squamous cell carcinoma (SCC)1. Since the association between cervical. SCC and human papillomavirus (HPV) types 16 and 18 has been proved by molecular studies2 and in animal. models the tumorigenic effect of HPV may differ according to the immunogenetic background,3 the presence of a given HLA type might help linking environmental. risk factors with individual. susceptibility to cervical. SCC. Subsequent studies however have reported different findings4,5 that could be in part explained by differences in HLA phenotype among populations.

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References

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Author information

Authors and Affiliations

  1. Department of Pathology of the University of Pavia and IRCCS Pol., San Matteo Pavia, Italy

    Patrizia Tenti, Solange Romagnoli, Enrico Silini, Rita Zappatore & Luciano Carnevali

  2. Immunohematology and Transfusion Service of the IRCCS Pol., San Matteo Pavia, Italy

    Miryam Martinetti & Cinzia Pizzochero

  3. Department of Obstetrics and Gynaecology of the University of Pavia and IRCCS Pol., San Matteo Pavia, Italy

    Luciana Babilonti

  4. Department of Genetics and Microbiology of the University of Pavia, Pavia, Italy

    Mariaclara Cuccia

Authors
  1. Patrizia Tenti
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  2. Miryam Martinetti
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  3. Solange Romagnoli
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  4. Enrico Silini
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  5. Cinzia Pizzochero
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  6. Rita Zappatore
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  7. Luciana Babilonti
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  8. Luciano Carnevali
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  9. Mariaclara Cuccia
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Editor information

Editors and Affiliations

  1. Department of Pathology, University of Cambridge, Cambridge, UK

    Margaret A. Stanley

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© 1994 Springer Science+Business Media New York

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Tenti, P. et al. (1994). Immunogenetic Study of Women with HPV Related Cancer of the Uterine Cervix. In: Stanley, M.A. (eds) Immunology of Human Papillomaviruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2449-6_30

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  • DOI: https://doi.org/10.1007/978-1-4615-2449-6_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6041-4

  • Online ISBN: 978-1-4615-2449-6

  • eBook Packages: Springer Book Archive

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