Pharmacology of The Ethynyl Estrogens in Various Countries

  • Joseph W. Goldzieher
Part of the Reproductive Biology book series (RBIO)


By 1985, there were already a dozen or so pharmacokinetic studies of ethynyl estradiol in different countries. The data were noteworthy for the great range of the various pharmacokinetic parameters.1


Oral Contraceptive Ethinyl Estradiol Oxidative Metabolite Contraceptive Steroid Ethynyl Estradiol 
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  1. 1.
    Newburger J, Goldzieher JW. Pharmacokinetics of ethynyl estradiol: current view. Contraception 32:33. 1985.PubMedCrossRefGoogle Scholar
  2. 2.
    Dyas J, et. al. A radioimmunoassay for ethinyl estradiol in plasma incorporating an immuno-sorbent, pre-assay purification procedure. Ann Clin Biochem 18:37. 1981.PubMedGoogle Scholar
  3. 3.
    Hiimpel M, et. al. Investigation of pharmacokinetics of ethynylestradiol to specific consideration of a possible first-pass effect on women. Contraception 19:421. 1979.CrossRefGoogle Scholar
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    Goldzieher JW, et. al. Human pharmacokinetics of ethynyl estradiol-3-sulfate and 17-sulfate. Steroids 51:63. 1988.PubMedCrossRefGoogle Scholar
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    Brody SA, Turkes A, Goldzieher JW. Pharmacokinetics of three bioequivalent norethindrone/ mestranol 50ug and three norethindrone/ethynyl estradiol 35ug formulations: are “low-dose” pills really lower? Contraception 40:269. 1989.PubMedCrossRefGoogle Scholar
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    Fotherby K, et. al. Pharmacokinetics of ethynylestradiol in women from different populations. Contraception 23:487. 1981.PubMedCrossRefGoogle Scholar
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    Goldzieher JW, Dozier TS, de la Pena A. Plasma levels and pharmacokinetics of ethynyl estrogens in various populations. I. Ethynyl estradiol. Contraception 21:1. 1980.PubMedCrossRefGoogle Scholar
  8. 8.
    Williams MC, Goldzieher JW. Chromatographic patterns of urinary ethynyl estrogen metabolites in various populations. Steroids 36:255. 1980.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1994

Authors and Affiliations

  • Joseph W. Goldzieher
    • 1
    • 2
  1. 1.Texas Technological UniversityAmarilloUSA
  2. 2.San AntonioUSA

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