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The Role of the α vB3 Integrin in Smooth Muscle Cell Migration

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Vascular Endothelium

Part of the book series: NATO ASI Series ((NSSA,volume 257))

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Abstract

Intimal hyperplasia is a key event in advanced atherosclerotic lesions. Thickening of the intimal layer of large muscular arteries may result from smooth muscle cells (SMC) that migrate from the muscular wall to the subluminal area and proliferate. The molecular basis for SMC motility is not known.

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References

  • Seftor, R.E.B., Seftor, EA., Gehlsen, K.R., Stetlerstevenson, W.G., Brown, P.D., Ruoslahti, E., and Hendrix, M.J.C., 1992, Role of the alphavbeta3 integrin in human melanoma cell invasion. Proc. Nati. Acad. Sci. U.S.A. 89:(5) 1557–1561.

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© 1993 Springer Science+Business Media New York

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Engel, L., Choi, E., Broschat, K., Gorka, C., Ryan, U., Callow, A. (1993). The Role of the α vB3 Integrin in Smooth Muscle Cell Migration. In: Catravas, J.D., Callow, A.D., Ryan, U.S. (eds) Vascular Endothelium. NATO ASI Series, vol 257. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2437-3_26

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  • DOI: https://doi.org/10.1007/978-1-4615-2437-3_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6035-3

  • Online ISBN: 978-1-4615-2437-3

  • eBook Packages: Springer Book Archive

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