Experimental Cell Transplantation and Gene Therapy Techniques in the Treatment of Liver Disease
Whole organ transplantation remains the only clinically effective method of treating acute and chronic liver failure due to specific genetic and other defects of liver function. However, there are several factors which limit the application of liver transplantation in the treatment of liver insufficiency: high cost, relatively high morbidity and limited organ donor availability. As a result, investigators have attempted to develop alternative methods to treat liver insufficiency due to genetic defects of liver function by using either isolated normal hepatocyte transplantation and/or in vitro and in vivo gene therapy techniques.
KeywordsLong Terminal Repeat Partial Hepatectomy Normal Hepatocyte Hepatocyte Transplantation Plasma Albumin Level
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