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The Cytoskeleton in the Differentiation of Myelin-Forming Cells

  • Peter J. Brophy
  • C. Stewart Gillespie
  • Bernadette M. Kelly
  • Demetrius A. Vouyiouklis
Part of the NATO ASI Series book series (NSSA, volume 258)

Abstract

The ensheathment of nerve fibres by oligodendrocytes and Schwann cells requires a dramatic change in cell morphology. Not only must these cells extend long processes in order to insulate axons but they must also migrate considerable distances to reach their targets. Since interactions between the cytoskeleton and the plasma membrane are known to control cell shape and movement, the cellular cytoskeleton must play a fundamental role in myelination.

Keywords

Glial Fibrillary Acidic Protein Schwann Cell Intermediate Filament Oligodendrocyte Progenitor Cell BioI 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Peter J. Brophy
    • 1
  • C. Stewart Gillespie
    • 1
  • Bernadette M. Kelly
    • 1
  • Demetrius A. Vouyiouklis
    • 1
  1. 1.Department of Biological and Molecular SciencesUniversity of StirlingStirlingScotland, UK

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