The Correlation Between Magnetic Resonance Imaging Abnormalities and other Aspects of Multiple Sclerosis with Particular Emphasis on Therapeutic Trials

  • Donald W. Paty
Part of the NATO ASI Series book series (NSSA, volume 258)


Magnetic resonance (MR) has had a major impact on the evaluation of patients with multiple sclerosis (MS). The most obvious area of influence has been on diagnosis. Diagnostically abnormal head scans can be seen in at least 90% of patients with clinically definite MS (CDMS). In addition, even though the spinal cord has been difficult to image in the past, techniques are improving. However, the findings on individual magnetic resonance imaging (MRI) scans do not usually correlate very well with the clinical (neurological) status of the patient, or with the prior clinical course. That lack of correlation should not be a surprise, however, because the same lack of correlation has always existed between the clinical history and pathological findings.


Multiple Sclerosis Expand Disability Status Scale Optic Neuritis Magnetic Resonance Imaging Evaluation Magnetic Resonance Imaging Lesion 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Donald W. Paty
    • 1
  1. 1.Division of NeurologyThe University of British ColumbiaCanada

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