Abstract
Positional confrontations are characteristic of the development of all multicellular organisms. In amphibian embryos, for example, formation of the mesoderm is dependent on contact between vegetal and animal pole cells (Symes et al. 1988). Later, mesodermal cells specified for dorsal and ventral fates interact to generate cells with intermediate fates (Dale & Slack 1987). In some insects, the trunk region develops from interactions between head and ‘tail’ structures (Cohen & Jürgens 1991). Finally, confrontations between differently-specified cells are required for limb outgrowth during development and regeneration (Bryant & Gardiner 1992).
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Bryant, S.V., Hayamizu, T.F., Gardiner, D.M. (1993). Patterning in Limbs: The Resolution of Positional Confrontations. In: Othmer, H.G., Maini, P.K., Murray, J.D. (eds) Experimental and Theoretical Advances in Biological Pattern Formation. NATO ASI Series, vol 259. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2433-5_6
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