Abstract
The goal-directed migration of cells is a wide-spread phenomenon in the development of organisms. Examples range from the aggregation of Dictyostelium amoeba during slug formation to the pathfinding of axonal growth cones during development of the nervous system. These examples typically share the characteristic that it is a population of single, isolated cells (or motile parts of cells as in the case of growth cones) which moves toward a pre-specified target. In contrast to this, the directional migration of the mesoderm during Xenopus gastrulation involves the movement of a multilayered coherent cell aggregate on a planar substrate.
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Winklbauer, R., Nagel, M., Selchow, A. (1993). Factors Controlling the Directionality of Mesoderm Cell Migration in the Xenopus Gastrula. In: Othmer, H.G., Maini, P.K., Murray, J.D. (eds) Experimental and Theoretical Advances in Biological Pattern Formation. NATO ASI Series, vol 259. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2433-5_31
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DOI: https://doi.org/10.1007/978-1-4615-2433-5_31
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