Abstract
The glycocalyx is a carbohydrate-rich cell coat that is present all along the apical membrane of the ocular surface epithelium and that is prominent at the tips of the microplicae.1–3 A previous study reports that the glycocalyx is adjacent to the mucous layer, the inner most layer of the tear fluid, and that the spread of the mucous layer over the microplicae of the apical cells is believed to be facilitated by the filamentous glycocalyx on the microplicae of the apical cell’s apical-most membrane.1,2 Therefore, the biochemical nature of the glycocalyx may be important to maintaining the tear fluid over the ocular surface epithelium. The biochemical nature of the glycocalyx and its interaction with or in the spread of mucus over the apical cells is, however, still unknown.
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Watanabe, H., Tisdale, A.S., Spurr-Michaud, S.J., Gipson, I.K. (1994). Developmental Appearance of a Component of the Glycocalyx of the Ocular Surface Epithelium in the Rat. In: Sullivan, D.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes. Advances in Experimental Medicine and Biology, vol 350. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2417-5_43
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DOI: https://doi.org/10.1007/978-1-4615-2417-5_43
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